Quarterly report pursuant to Section 13 or 15(d)

Note 2 - Summary of Significant Accounting Policies - Antidilutive Securities (Details)

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Note 2 - Summary of Significant Accounting Policies - Antidilutive Securities (Details) - shares
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Employee Stock Option [Member]    
Stock options to purchase common stock (in shares) 4,298,565 2,489,979
Common Stock Warrants [Member]    
Stock options to purchase common stock (in shares) 642,622 642,622
Restricted Stock [Member]    
Stock options to purchase common stock (in shares) 60,000